Details of the Drug

General Information of Drug (ID: DMC56T4)

Drug Name
RAF265
Synonyms
RAF265; 927880-90-8; CHIR-265; RAF 265; RAF-265; CHIR 265; RAF265 (CHIR-265); 1-Methyl-5-[[2-[5-(trifluoromethyl)-1h-imidazol-2-yl]-4-pyridinyl]oxy]-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine; CHIR265; RAF265(CHIR-265); UNII-8O434L3768; 8O434L3768; 1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine; 1-Methyl-5-({2-[5-(Trifluoromethyl)-1h-Imidazol-2-Yl]pyridin-4-Yl}oxy)-N-[4-(Trifluoromethyl)phenyl]-1h-Benzimidazol-2-Amine; PubChem22594
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 518.4
Logarithm of the Partition Coefficient (xlogp) 5.4
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C24H16F6N6O
IUPAC Name
1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine
Canonical SMILES
CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
InChI
InChI=1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,35)(H,33,34)
InChIKey
YABJJWZLRMPFSI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11656518
ChEBI ID
CHEBI:91451
CAS Number
927880-90-8
UNII
8O434L3768
DrugBank ID
DB05984
TTD ID
D03AND
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Melanoma
ICD Disease Classification 2C30
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 2 (KDR) DTT KDR 1.98E-01 0.11 0.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 131 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 1.5265 4.892 1.374 30.6086
JM1 CTRP2 2.7409 4.6067 2.7069 22.1225
EoL-1 CTRP2 -10.6037 -8.9111 -10.6037 99.4217
HDLM-2 CTRP2 -2.4008 8.891 -4.0808 53.8964
Peer CTRP2 -1.9153 1.034 -1.9224 53.0056
JVM-3 CTRP2; CCLE -1.8568 3.2103 -2.0773 49.3264
KE-37 CTRP2 -1.7824 2.774 -1.8755 52.0311
Pfeiffer CCLE -1.6141 2.6379 -1.9415 40.6584
NU-DUL-1 CTRP2 -1.4119 4.7268 -1.7747 49.7165
MOLT-16 CCLE -1.3243 1.7412 -1.4447 37.603
697 CTRP2; CCLE -1.1439 2.4998 -1.1868 47.9348
MHH-CALL-3 CTRP2 -1.1012 8.2615 -2.4547 48.3077
SIG-M5 CTRP2; CCLE -1.082 -0.3103 -1.082 47.4771
SEM CTRP2 -1.0091 2.6488 -1.0565 47.0578
LAMA-84 CTRP2 -0.9991 3.7413 -1.158 47.1102
SK-MM-2 CCLE -0.9899 4.2867 -1.7629 37.0171
GA-10 CTRP2 -0.9841 2.3124 -1.0115 46.8677
KE-97 CTRP2; CCLE -0.9587 3.7804 -1.1203 46.8571
KO52 CTRP2; CCLE -0.8734 3.292 -0.9695 46.2361
RS4;11 CTRP2 -0.7778 4.4652 -1.0368 45.8308
EM-2 CTRP2; CCLE -0.5409 2.6447 -0.5714 43.9455
JURL-MK1 CTRP2 -0.5142 3.4019 -0.6019 43.8869
DB CTRP2 -0.3989 7.9018 -1.5698 44.6478
NCO2 CTRP2; CCLE -0.3147 2.8355 -0.3483 42.4548
L-363 CCLE -0.3084 3.6064 -0.7927 30.492
P31/FUJ CTRP2; CCLE -0.2197 5.8574 -0.7417 42.7892
NALM-6 CTRP2 -0.1584 4.4432 -0.3645 41.8208
Kasumi-2 CTRP2; CCLE -0.1307 3.7632 -0.2362 41.4153
KG-1 CCLE -0.1015 2.7065 -0.3093 27.5512
Ku812 CTRP2; CCLE -0.0779 2.4393 -0.0887 40.8204
REC-1 CTRP2 0.1417 5.5013 -0.2576 40.325
CML-T1 CTRP2 0.1487 3.2093 0.1088 39.3986
Mino CCLE 0.1691 3.8582 -0.3601 26.6876
Karpas-422 CTRP2; CCLE 0.2467 2.2952 0.243 38.6371
ALL-SIL CCLE 0.2703 2.0252 0.2196 23.6644
Hs 611.T CTRP2 0.3051 6.4732 -0.3412 39.8368
MEG-01 CCLE 0.4329 3.7288 -0.0297 24.1559
SET-2 CTRP2 0.4479 4.1711 0.3276 37.6488
L-428 CTRP2; CCLE 0.4699 5.9728 -0.0198 38.468
MHH-CALL-4 CTRP2 0.5116 12.634 -2.5242 42.2798
OCI-Ly19 CTRP2 0.5567 6.6293 -0.1139 38.3507
P12-Ichikawa CTRP2; CCLE 0.5964 3.747 0.5336 36.4947
AML-193 CTRP2 0.6341 4.0686 0.5389 36.3436
RPMI-6666 CTRP2 0.6866 5.0726 0.431 36.4677
Jurkat CTRP2; CCLE 0.723 7.9532 -0.377 38.2965
OCI-AML-2 CCLE 0.7945 1.7511 0.789 18.9652
CMK-86 CCLE 0.8873 5.7179 -0.3619 24.0147
Ki-JK CTRP2 0.902 6.9367 -0.1045 32.954
KMS-20 CTRP2 0.9574 5.9025 0.531 35.1966
KMS-12-BM CCLE 1.0576 4.2753 0.434 19.6261
MOLT-3 CTRP2 1.1751 2.6758 1.174 32.4435
RPMI-8402 CTRP2; CCLE 1.1892 4.6559 1.0501 32.8029
EHEB CTRP2 1.1933 7.9038 -0.178 32.1572
MJ CTRP2; CCLE 1.2021 5.8309 0.8166 33.4906
MEC-1 CCLE 1.288 7.4411 -0.7699 24.4448
SUP-B15 CTRP2 1.3004 5.3929 1.0294 32.4905
KMS-34 CTRP2; CCLE 1.3047 3.6821 1.2779 31.666
HuT 78 CTRP2; CCLE 1.3223 4.6051 1.2006 31.8627
Mono-Mac-1 CCLE 1.4649 8.1469 -0.9429 24.5947
NU-DHL-1 CTRP2 1.5429 5.1776 1.3384 30.6727
Daudi CTRP2 1.5463 3.4118 1.5379 29.9951
ST486 CTRP2 1.6573 4.3929 1.5859 29.467
Ri-1 CTRP2 1.719 12.0445 -1.0346 36.2464
DND-41 CTRP2 1.7561 3.7362 1.7408 28.6203
KM-H2 CTRP2 1.8027 8.5317 0.5597 32.219
OCI-Ly3 CTRP2 1.8071 6.1991 1.3769 29.6788
JVM-2 CTRP2 1.8102 11.2802 -0.5988 35.0758
Namalwa CTRP2 1.8328 5.842 1.5018 29.1782
SU-DHL-8 CTRP2; CCLE 1.8338 4.2701 1.7851 28.2153
Karpas-299 CCLE 1.8377 3.4011 1.6032 11.0718
PF-382 CTRP2 1.8401 6.4953 1.3254 29.7422
Ci-1 CCLE 1.8707 3.3076 1.6717 10.6176
DoHH2 CTRP2; CCLE 1.8824 5.6416 1.4138 24.3342
Karpas-620 CCLE 1.9424 5.7727 0.657 15.5632
HT CTRP2; CCLE 1.9817 5.5513 1.735 27.9064
TF-1 CTRP2 1.9925 5.9149 1.6572 28.1381
SUP-T11 CTRP2 2.0048 5.6066 1.7472 27.7908
KMS-18 CTRP2 2.0838 5.265 1.9072 26.9874
BL-70 CTRP2; CCLE 2.1078 4.3209 2.0682 26.3591
KCL-22 CTRP2; CCLE 2.1507 6.1355 1.7699 27.2492
EB1 CTRP2; CCLE 2.243 4.6126 2.1812 25.534
SU-DHL-1 CTRP2 2.2968 4.0251 2.2835 25.0116
SUP-M2 CTRP2; CCLE 2.3234 4.3298 2.2929 24.892
MOLM-13 CTRP2 2.3275 5.2126 2.1811 25.2621
MOLP-8 CTRP2; CCLE 2.3476 5.0806 2.2263 25.0416
U-937 CCLE 2.3511 6.4926 0.6873 14.1983
F-36P CTRP2; CCLE 2.3823 9.8891 0.6003 30.2916
WSU-DLCL2 CTRP2 2.4384 7.1381 1.7642 26.377
A3/Kawakami CTRP2 2.4923 4.2643 2.4728 23.7299
M-07e CTRP2 2.5124 7.3643 1.7631 26.1561
HEL 92.1.7 CCLE 2.5617 3.5695 2.3 5.0461
BL-41 CCLE 2.5706 3.5255 2.3287 4.8693
SU-DHL-10 CTRP2; CCLE 2.5851 3.5795 2.5847 23.0477
BDCM CCLE 2.6267 3.7215 2.2951 4.8623
HEL CTRP2 2.651 10.9217 0.4136 30.0316
DEL CTRP2; CCLE 2.6608 3.1594 2.6608 22.5422
SUP-HD1 CTRP2 2.6989 6.5221 2.2526 23.8558
KMM-1 CTRP2; CCLE 2.7137 7.41 1.6149 20.9912
SU-DHL-6 CTRP2; CCLE 2.7565 5.9761 2.4747 22.885
SU-DHL-4 CTRP2; CCLE 2.8663 5.361 2.7358 21.6198
CA46 CTRP2 2.874 6.8357 2.34 23.0147
KMS-11 CCLE 2.9092 10.3908 -0.7713 19.6952
KMS-26 CTRP2; CCLE 3.0133 4.6036 2.9917 20.2659
TALL-1 [Human adult T-ALL] CTRP2 3.0469 5.7175 2.8562 20.6295
KMS-27 CTRP2 3.0747 5.9048 2.8405 20.5996
JeKo-1 CTRP2 3.0862 7.7378 2.2356 22.7768
EB2 CCLE 3.2228 4.7884 2.284 3.3597
Granta-519 CTRP2; CCLE 3.2349 6.5066 2.8407 20.1142
K-562 CTRP2 3.2695 5.822 3.0738 19.166
MOTN-1 CTRP2 3.3603 6.4471 2.9961 19.1718
HH [Human lymphoma] CCLE 3.5976 8.0772 0.9406 9.715
RL CTRP2 3.7519 6.5509 3.3879 16.5715
MC116 CTRP2; CCLE 3.8226 4.5446 3.8219 14.8041
U266B1 CTRP2 3.8423 11.3869 1.3722 23.8055
SUP-T1 CCLE 3.8864 6.1745 2.0767 3.1794
P3HR-1 CTRP2; CCLE 4.0485 8.7503 2.8062 17.9949
LP-1 CTRP2; CCLE 4.0714 6.1767 3.8536 13.911
OPM-2 CTRP2; CCLE 4.1402 5.8251 4.0218 13.0954
OCI-M1 CTRP2 4.2231 6.5694 3.8921 13.3213
EJM CTRP2 4.3152 7.6214 3.5765 14.2785
JM-1 CCLE 4.3269 6.0184 2.4006 1.0854
Toledo CCLE 4.6088 6.7662 2.2284 1.4973
JJN-3 CTRP2 4.6964 8.2081 3.7042 12.7888
AMO1 CTRP2; CCLE 4.9529 8.2056 3.9591 11.1265
OCI-Ly10 CTRP2; CCLE 5.221 7.8061 4.4094 8.6463
HPB-ALL CTRP2 5.6728 11.9996 2.7517 14.4561
CMK CTRP2 5.8223 10.7061 3.526 11.0032
KHM-1B CTRP2; CCLE 6.3021 9.5613 3.7284 3.7738
Raji CTRP2; CCLE 8.1198 9.1545 5.7151 0.038
Reh CTRP2 8.1981 9.3576 5.6742 0.0589
OCI-AML-5 CTRP2; CCLE 10.8051 19.462 2.765 6.6871
⏷ Show the Full List of 131 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 3.7757 14.4425 -0.1684 28.5877
TE8 CTRP2 3.834 7.0533 3.2972 16.6753
KYSE-140 CTRP2 0.2481 10.6953 -1.9599 42.5551
OE21 CCLE 0.4574 4.0587 -0.1218 24.4879
OE33 CCLE 1.3697 5.9024 0.0376 20.4921
KYSE-520 CCLE 1.942 4.904 1.0679 13.4332
TE-6 CTRP2 2.7226 8.593 1.5058 26.4181
TE-10 CTRP2 2.8101 9.0309 1.4127 26.4783
KYSE-30 CTRP2; CCLE 2.8529 3.4996 2.8528 21.2625
TE-9 CTRP2; CCLE 2.8778 7.3131 2.1747 23.6031
KYSE-410 CTRP2; CCLE 2.9367 9.5956 1.298 26.4979
TE-14 CTRP2 3.6998 7.6888 2.9044 18.5462
TE-11 CTRP2 3.875 11.9949 1.1121 24.5867
TE-4 CTRP2 3.989 7.6936 3.2061 16.5963
KYSE-180 CTRP2 4.2878 12.3309 1.3393 22.8066
KYSE-150 CTRP2; CCLE 4.885 8.0897 3.9464 11.3445
KYSE-510 CTRP2 5.4501 7.9142 4.5775 7.4179
COLO 680N CTRP2 6.368 13.6522 2.5066 14.0423
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -0.3836 9.5205 -2.1523 45.12
IPC-298 CCLE -2.1087 3.7001 -2.7811 45.1051
WM88 CTRP2; CCLE -1.3126 1.3582 -1.3183 49.0174
SK-MEL-1 CTRP2 -1.1679 4.6798 -1.5004 48.2693
Malme-3M CTRP2; CCLE -0.9762 2.6278 -1.021 46.8392
G-361 CCLE -0.8174 2.8368 -1.1226 34.0268
WM1799 CCLE -0.7718 5.5147 -1.9982 36.6988
SK-MEL-5 CCLE -0.6079 2.9526 -0.9246 32.3143
CHL-1 CCLE -0.459 4.3538 -1.2151 32.7892
Mel Ho CTRP2; CCLE -0.4424 4.7695 -0.7319 43.7809
COLO 679 CCLE -0.1198 3.3239 -0.4984 28.459
UACC-62 CCLE 0.2237 3.1284 -0.0658 25.1407
COLO 829 CTRP2 0.3124 5.6855 -0.1168 39.3172
WM983B CTRP2; CCLE 0.3645 5.5013 -0.0148 38.8696
HMCB CCLE 0.4051 5.5205 -0.7693 27.552
K029AX CCLE 0.4199 6.5228 -1.1972 29.2033
SK-MEL-30 CCLE 0.4746 3.9204 -0.0526 24.1019
WM266-4 CTRP2; CCLE 0.4788 3.8682 0.3974 37.3309
WM115 CTRP2; CCLE 0.5264 2.3438 0.5243 36.7689
Hs 940.T CTRP2 0.5728 10.4799 -1.5303 40.8481
SF8657 CCLE 0.6232 6.6504 -1.0507 27.8904
HT-144 CTRP2; CCLE 1.0045 5.4165 0.7021 34.529
RVH-421 CTRP2; CCLE 1.2157 4.0925 1.1518 32.3815
A-375 CTRP2; CCLE 1.263 4.7215 1.1188 32.33
SK-MEL-2 CCLE 1.3428 5.5426 0.1769 19.9029
WT2-iPS CTRP2; CCLE 1.4038 4.6619 1.2795 31.3298
Hs 944.T CTRP2; CCLE 1.4559 9.8719 -0.353 35.6729
LOX-IMVI CCLE 1.4902 3.8719 1.053 15.0309
MeWo CTRP2; CCLE 1.5295 5.286 1.3016 30.839
SK-MEL-24 CTRP2; CCLE 1.5718 7.5591 0.6795 32.6356
UACC-257 CCLE 1.7145 4.7743 0.9002 15.0341
Hs 895.T CTRP2; CCLE 1.7777 7.1556 1.0433 30.8533
MDA-MB-435S CTRP2; CCLE 2.0791 8.4404 0.889 30.3658
Hs 938.T CCLE 2.2421 4.6874 1.4639 10.4226
Hs 695T CCLE 2.2995 8.1514 -0.1805 18.687
Hs 294T CTRP2; CCLE 2.6095 8.2818 1.5139 26.7244
IGR-37 CTRP2; CCLE 2.6552 8.3217 1.5461 26.4793
SK-MEL-3 CTRP2 2.7628 7.1945 2.0942 24.2332
SK-MEL-28 CTRP2 3.6246 7.821 2.7712 19.2615
A101D CTRP2 3.768 11.6156 1.1914 24.6003
Hs 852.T CTRP2; CCLE 4.0899 14.2362 0.2241 26.7498
RPMI-7951 CTRP2; CCLE 4.0978 9.2532 2.6261 18.5677
CJM [Human melanoma] CTRP2 4.6831 10.2863 2.7042 16.8284
IGR-39 CTRP2; CCLE 4.8271 12.2537 1.8748 19.6493
A2058 CTRP2; CCLE 5.0389 9.0143 3.6562 12.1585
WM793 CTRP2; CCLE 5.3217 13.9692 1.4647 20.0062
Hs 839.T CTRP2 5.4978 9.3708 3.9063 10.0979
Hs 934.T CTRP2 5.5688 7.1028 5.0807 5.0728
Hs 688(A).T CTRP2 5.7147 6.2738 5.6036 2.6068
Hs 936.T CTRP2; CCLE 6.4572 12.8243 2.992 11.9615
SK-MEL-31 CTRP2; CCLE 6.4827 14.576 2.1381 15.2255
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 2.3468 7.3208 1.6004 27.2226
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-SH CTRP2; CCLE 1.0092 5.9146 0.5842 34.8587
IMR-32 CTRP2; CCLE 1.1978 2.9564 1.1941 32.3009
CHP-212 CTRP2; CCLE 1.4063 4.6194 1.2886 31.2916
SiMa CCLE 1.6005 3.7096 1.2337 13.7435
MHH-NB-11 CTRP2 1.7429 3.8447 1.7218 28.7276
NH-6 CTRP2 1.7535 5.5974 1.4757 29.5231
SK-N-BE(2) CTRP2; CCLE 1.7796 6.1166 1.3702 29.7901
KP-N-SI9s CCLE 1.8418 6.6674 0.1299 18.5373
SK-N-FI CCLE 1.9384 6.3703 0.365 17.068
SK-N-AS CTRP2 3.2372 7.0191 2.6685 20.7424
SK-N-DZ CTRP2; CCLE 3.72 6.8692 3.2428 17.2051
CHP-126 CTRP2 4.8646 8.5584 3.7066 12.3662
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 1.6958 7.542 0.8193 31.8106
HuCC-T1 CCLE 1.7137 6.1803 0.2423 18.3778
SNU-1196 CTRP2 3.0182 5.9565 2.7654 21.0415
SNU-308 CTRP2 3.1352 8.2708 2.0719 23.2351
SNU-869 CTRP2 4.4626 7.1782 3.916 12.5584
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-ES-1 CTRP2; CCLE -0.0189 4.8743 -0.2939 41.0741
SK-ES-1 CTRP2; CCLE 0.0149 5.8695 -0.4889 41.3267
A-673 CTRP2; CCLE 0.2178 4.1153 0.0896 39.1858
SK-N-MC CTRP2 0.9764 4.7365 0.8079 34.3045
Hs 888.T CTRP2 2.1953 17.933 -3.3489 38.4836
HOS CTRP2; CCLE 2.2071 4.7344 2.128 25.8323
SJSA-1 CTRP2; CCLE 3.368 8.0651 2.4012 21.3677
MG-63 CTRP2; CCLE 3.374 10.987 1.1041 25.9222
TC-71 CCLE 3.5293 6.0393 1.8957 4.7883
CAL-78 CTRP2; CCLE 3.7693 11.695 1.1547 24.7175
Hs 822.T CTRP2 5.3262 5.9073 5.2933 4.8976
SaOS-2 CTRP2; CCLE 6.5679 12.5752 3.2043 10.903
SW1353 CTRP2; CCLE 7.2296 18.5766 0.0018 17.0023
U2OS CTRP2; CCLE 7.9815 18.9922 0.3407 14.6297
G-292 clone A141B1 CTRP2 9.6581 19.0737 2.2391 9.8493
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 -0.7222 2.2827 -0.7415 45.1226
BT-549 CCLE 0.1075 5.6416 -1.1297 30.1401
MDA-MB-415 CCLE 0.9592 6.6108 -0.698 25.2482
MDA-MB-468 CTRP2; CCLE 1.3381 5.9996 0.9205 32.7039
MDA-MB-436 CCLE 1.3425 4.9328 0.4514 18.5457
Hs 578Bst CTRP2 1.4541 11.6555 -1.1285 37.2488
Hs 739.T CCLE 1.4587 7.7858 -0.7736 23.906
EFM-19 CCLE 1.4671 4.2939 0.8563 16.0919
HCC1806 CTRP2; CCLE 1.8465 7.2821 0.7638 26.8869
BT-20 CTRP2; CCLE 2.0849 5.3254 1.8963 27.0216
MDA-MB-157 CCLE 2.2671 6.1519 0.7782 13.9643
MDA-MB-453 CTRP2; CCLE 2.3241 6.0689 1.9776 25.9827
UACC-812 CCLE 2.3623 3.3499 2.1848 6.3136
HCC1500 CTRP2 2.4355 6.8148 1.8714 26.011
HCC70 CCLE 2.6487 4.5124 1.9342 6.7131
CAL-85-1 CTRP2; CCLE 2.6861 8.5178 1.4986 26.5499
HCC1187 CCLE 2.7858 4.1152 2.2552 4.6025
AU565 CTRP2; CCLE 2.8862 5.9297 2.6284 21.937
HDQ-P1 CCLE 2.8887 7.2293 0.7919 12.1949
ZR-75-30 CTRP2; CCLE 3.2413 7.5194 2.4859 21.4088
SK-BR-3 CTRP2; CCLE 3.3278 7.1539 2.7169 20.301
MDA-MB-175-VII CCLE 3.341 7.1359 1.2089 8.8748
HMC-1-8 CTRP2; CCLE 3.4622 6.3525 3.1366 18.354
MDA-MB-361 CTRP2 3.6624 5.4244 3.5841 16.1366
HCC1954 CTRP2; CCLE 3.7371 8.9535 1.9164 16.9652
HCC1569 CCLE 4.1188 6.7737 1.9441 3.4629
HCC1419 CTRP2 4.5972 7.499 3.9211 12.1785
HCC1937 CTRP2 4.7006 10.2508 2.738 16.6544
T-47D CTRP2; CCLE 5.026 11.4468 2.4537 17.0193
ZR-75-1 CTRP2; CCLE 5.7259 10.4363 3.5777 10.9851
CAL-120 CTRP2 5.7829 6.8945 5.3857 3.3186
HCC1395 CTRP2 5.8871 13.215 2.3272 15.6738
KPL-1 CTRP2 5.9852 19.0282 -0.4969 24.5455
BT-474 CTRP2; CCLE 6.0407 8.7063 4.7104 5.6145
CAMA-1 CTRP2; CCLE 6.5405 15.1778 1.1641 14.0761
MCF-7 CTRP2; CCLE 6.6075 11.6201 2.9504 6.6282
Hs 578T CTRP2; CCLE 7.2139 20.8918 -0.4286 22.0597
CAL-148 CTRP2 7.2468 13.2231 3.4012 8.9472
JIMT-1 CTRP2 7.3269 13.9315 3.112 9.9722
BT 428 CTRP2 -0.901 6.9251 -1.793 47.0821
BT 416 CTRP2 -0.687 12.4993 -3.6977 47.143
BT 239 CTRP2 0.4279 3.1139 0.4034 37.4963
BT 286 CTRP2 0.6344 7.0534 -0.1631 38.1648
BT 231 CTRP2 0.914 4.0287 0.8399 34.4207
BT 248 CTRP2 0.9721 4.999 0.7553 34.4822
BT 228 CTRP2 1.0235 4.4578 0.9025 33.8435
BT 271 CTRP2 1.0538 4.7265 0.893 33.7688
BT 131 CTRP2 1.5901 5.8148 1.244 30.8271
BT 504 CTRP2 1.7611 4.5711 1.6743 28.8282
BT 172 CTRP2 1.9254 7.3409 1.1387 30.0735
BT147 CTRP2 1.9672 7.3425 1.1832 29.7971
BT 216 CTRP2 2.0063 12.1176 -0.7788 34.8598
BT 159 CTRP2 2.0398 6.6896 1.4823 28.5806
BT 359 CTRP2 2.0662 6.4165 1.5958 28.1129
BT 187 CTRP2 2.1105 7.4882 1.2855 29.011
BT 482 CTRP2 2.1315 9.3044 0.5906 31.0869
BT 330 CTRP2 2.3873 8.0217 1.3812 27.8392
BT 245 CTRP2 2.3928 4.5449 2.3468 24.4823
BT 139 CTRP2 2.5294 2.9841 2.5294 23.4177
BT 440 CTRP2 3.5219 11.9569 0.7911 26.5165
BT 422 CTRP2 3.5237 9.2871 2.0334 22.3044
BT 232 CTRP2 3.7816 8.4884 2.6507 19.2967
BT 444 CTRP2 3.9791 13.4718 0.4949 26.241
BT 340 CTRP2 4.122 14.8795 -0.0623 27.4598
BT 333 CTRP2 4.3775 9.9795 2.5596 18.1275
BT 328 CTRP2 5.7646 11.6835 2.9884 13.3203
BT 498 CTRP2 6.2405 25.1661 -3.3535 30.0618
BT 320 CTRP2 7.8993 18.0051 1.5308 14.9056
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.5187 7.2089 1.8258 25.918
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DBTRG-05MG CTRP2; CCLE 1.0925 9.4426 -0.5568 37.3419
SNU-466 CTRP2 1.2822 4.384 1.1886 32.0365
SW1783 CTRP2 1.4626 6.8267 0.8105 32.616
M059J CCLE 1.6882 5.1361 0.7086 16.0998
KNS-60 CCLE 1.9779 7.5988 -0.1983 19.7102
SF539 CTRP2 2.0103 4.2212 1.9744 26.9964
GMS-10 CCLE 2.1598 6.1991 0.6557 14.9161
GB-1 CTRP2; CCLE 2.1908 12.0973 -0.5848 33.8914
1321N1 CCLE 2.2204 7.3363 0.1522 17.2997
DK-MG CCLE 2.3453 8.1138 -0.1211 18.2744
H4 CCLE 2.434 8.4047 -0.1874 18.3402
SF268 CTRP2 2.4808 6.1706 2.1202 24.9943
KNS-42 CTRP2; CCLE 2.5938 6.8619 2.0275 24.9781
KNS-81 CTRP2; CCLE 2.6081 6.6998 2.0968 24.6881
LN-18 CTRP2; CCLE 2.6366 6.9414 2.0469 24.7799
D283 Med CTRP2 3.0853 9.1421 1.6493 24.883
T98G CTRP2; CCLE 3.3435 7.8149 2.4775 21.1509
ONS-76 CTRP2; CCLE 3.3627 10.8872 1.1395 25.8378
U-118MG CTRP2; CCLE 3.5023 9.0201 2.1305 22.0056
MOG-G-CCM CCLE 3.5421 7.4763 1.196 8.4899
Hs 683 CTRP2; CCLE 3.5717 8.8944 2.257 21.3488
LN-229 CTRP2; CCLE 3.8725 12.0892 1.0644 24.7479
GOS-3 CTRP2 3.9752 10.03 2.1436 20.7154
42-MG-BA CTRP2 4.0382 8.9093 2.7239 18.3415
Daoy CTRP2; CCLE 4.1313 10.6559 1.9996 20.8553
SF126 CTRP2; CCLE 5.2877 10.8456 2.9874 14.3289
U-251MG CTRP2 5.3102 10.0076 3.422 12.5089
YKG-1 CTRP2 5.3136 11.0872 2.8907 14.6613
A-172 CTRP2; CCLE 5.432 13.183 1.9527 18.025
CAS-1 CTRP2; CCLE 5.7893 18.7767 -0.5356 25.0365
SNB-75 CTRP2 5.8828 7.7034 5.0767 4.3908
YH-13 CTRP2 6.119 14.2925 1.9824 16.5047
GaMG CTRP2 6.1579 12.5347 2.8933 12.9225
M059K CTRP2 6.2931 11.553 3.4945 10.2203
SNU-738 CTRP2 6.3012 9.715 4.4185 6.3539
KALS-1 CTRP2; CCLE 6.6411 17.538 0.787 19.5833
KG-1-C CTRP2 6.6767 17.9888 0.5906 20.1276
8-MG-BA CTRP2 6.869 12.7357 3.3587 9.747
NMC-G1 CTRP2 7.1078 16.5987 1.6252 15.9338
SW1088 CTRP2; CCLE 7.1775 21.5542 -0.7876 23.0548
SF295 CTRP2; CCLE 7.7501 18.9724 0.941 17.1103
Becker CTRP2 7.9178 19.8187 0.6494 17.7449
U-87MG ATCC CTRP2; CCLE 8.3734 18.52 0.8383 12.3002
TM-31 CTRP2 8.4825 20.166 0.8981 16.0493
SNU-1105 CTRP2 11.9723 34.0538 -4.1717 20.7584
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -3.6072 1.6491 -3.6904 62.9676
HEC-151 CCLE -1.1397 4.7416 -2.0895 38.6387
HEC-59 CTRP2; CCLE 0.1467 4.4546 -0.038 39.7963
RL95-2 CTRP2; CCLE 0.3602 6.9966 -0.7077 36.6191
KLE CTRP2; CCLE 0.9081 9.9309 -0.9509 38.7408
MFE-280 CCLE 1.5103 4.0733 0.9933 15.2563
JHUEM-1 CTRP2 1.8592 2.9039 1.8591 27.8828
MFE-296 CTRP2; CCLE 1.9234 5.2969 1.7269 28.1217
AN3-CA CCLE 2.0496 4.113 1.5365 10.6631
HEC-251 CTRP2; CCLE 2.6692 9.366 1.123 27.8413
EFE-184 CTRP2; CCLE 2.9484 6.1932 2.6239 21.7632
HEC-1-A CTRP2; CCLE 3.0186 7.794 2.1417 23.3138
ESS-1 CTRP2 3.4946 6.8081 3.0212 18.6847
TEN CCLE 3.5519 6.4941 1.6888 5.8426
HEC-1-B CTRP2; CCLE 4.0497 13.9338 -0.2542 24.2707
HEC-50B CTRP2 4.5517 8.2869 3.5233 13.8764
MFE-319 CTRP2 4.9726 10.9518 2.6488 16.3779
HEC-108 CTRP2 5.3848 15.4044 0.804 22.0559
EN CTRP2; CCLE 6.6315 11.1013 3.987 7.5728
HEC-265 CTRP2; CCLE 6.6862 9.3468 4.8927 3.7338
HEC-6 CTRP2; CCLE 7.5807 16.1051 2.2299 12.9408
Ishikawa (Heraklio) 02 ER- CTRP2 7.4738 8.5944 5.6756 0.2001
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACHN CTRP2; CCLE -0.2119 10.068 -2.1867 44.4841
UO-31 CTRP2 0.0638 4.948 -0.2191 40.5633
SNU-1272 CTRP2 2.7783 5.2871 2.6546 22.182
CAL-54 CTRP2 3.1375 13.8596 -0.4885 31.0248
KMRC-20 CTRP2 3.7453 7.4476 3.0498 17.8652
VMRC-RCZ CTRP2; CCLE 3.849 9.0628 2.4635 19.8342
786-O CTRP2; CCLE 4.9696 10.9101 2.6665 16.3151
BFTC-909 CTRP2; CCLE 5.1574 8.7674 3.8878 10.9336
RCC10RGB CTRP2 5.7199 7.0638 5.2442 4.047
769-P CTRP2; CCLE 6.2176 14.5056 1.2524 14.3226
A-498 CTRP2 6.2906 12.6924 2.9233 12.5487
KMRC-1 CTRP2; CCLE 6.6206 15.4275 1.8239 16.1177
Caki-1 CTRP2 6.7624 15.0222 2.1389 14.7029
OS-RC-2 CTRP2 7.2096 17.9165 0.3115 15.9968
KMRC-2 CTRP2; CCLE 7.3587 16.1033 2.0639 13.925
TUHR10TKB CTRP2 7.8767 9.305 5.5747 0.251
VMRC-RCW CTRP2; CCLE 8.1443 19.0368 1.2044 15.602
Caki-2 CTRP2; CCLE 8.6243 21.2478 0.471 17.1422
KMRC-3 CTRP2 9.6736 24.8696 -0.5418 18.4049
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320 CTRP2; CCLE -2.042 3.1706 -2.194 53.5559
HCT 15 CTRP2; CCLE -0.479 3.6855 -0.5966 43.7149
COLO201 CCLE -0.4486 2.6974 -0.6855 30.6363
SW948 CTRP2 -0.4309 3.447 -0.5187 43.3426
SNU-81 CTRP2 0.2822 4.9503 0.0173 39.1176
CL-11 CTRP2 0.3339 9.0195 -1.1935 41.2277
RKO CCLE 0.7489 4.0706 0.186 21.9478
SW480 CCLE 1.542 5.9222 0.1979 19.1454
SW1417 CTRP2; CCLE 1.6844 4.7575 1.5657 29.4463
SK-CO-1 CTRP2; CCLE 1.7196 5.1333 1.5386 29.4223
SW620 CCLE 1.7387 4.7615 0.9303 14.8001
LS180 CTRP2 1.8911 8.4539 0.6843 31.5749
SW48 CCLE 2.1123 4.9123 1.2312 12.0462
COLO 678 CTRP2; CCLE 2.2984 8.0665 1.2691 28.481
LS513 CTRP2; CCLE 2.3242 5.454 2.129 25.4536
LS411N CTRP2; CCLE 2.4396 6.3816 2.0134 25.4988
NCI-H747 CTRP2; CCLE 2.4963 5.407 2.3258 24.2227
SNU-175 CTRP2 2.5516 10.0514 0.7029 29.4859
SNU-C1 CTRP2 2.5859 7.335 1.8529 25.6203
SW403 CCLE 2.7785 3.7596 2.4228 3.726
T84 CTRP2; CCLE 2.785 6.296 2.4156 23.0094
SNU-1033 CTRP2 3.0017 8.0972 2.0026 23.8661
SNU-C2B CCLE 3.0602 5.3104 1.8945 5.842
LS123 CCLE 3.1277 6.3573 1.4266 8.2089
COLO205 CTRP2; CCLE 3.2968 8.352 1.7772 18.6973
SNU-C5 CTRP2 3.4934 18.644 -2.49 34.1381
CCK-81 CCLE 3.5929 6.6145 1.6599 5.9109
C2BBe1 CCLE 3.7472 9.2422 0.4776 11.767
CW-2 CTRP2 3.8222 8.2662 2.7891 18.6563
KM12 CTRP2 3.87 6.7781 3.4372 16.0445
DLD-1 CTRP2 3.9695 7.6515 3.2031 16.6606
SNU-C2A CTRP2; CCLE 5.106 15.1474 0.0441 20.924
OUMS-23 CTRP2 5.1814 8.4489 4.0644 10.1524
HCC-56 CTRP2; CCLE 5.3538 8.7717 4.0698 9.7356
HCT 8 CTRP2 5.3784 6.0373 5.3195 4.6425
SNU-C4 CTRP2 5.6294 6.2763 5.5123 3.1937
SNU-503 CTRP2 6.4052 14.4134 2.1566 15.3034
HT115 CTRP2 6.5848 11.2493 3.8775 8.1078
HT-29 CTRP2; CCLE 8.0002 9.2332 5.6469 0.1129
HCT 116 CTRP2; CCLE 8.1252 9.3625 5.6471 0.0921
MDST8 CTRP2 8.4501 20.5524 0.6845 16.7681
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-HEP-1 CTRP2; CCLE -0.5051 4.5217 -0.7525 44.107
Hep 3B2.1-7 CTRP2; CCLE 0.5249 3.5258 0.4286 32.599
Hep-G2 CCLE 1.1905 4.3677 0.5362 18.651
Li-7 CTRP2 1.4933 9.3676 -0.1043 34.974
JHH-5 CTRP2; CCLE 1.5454 2.7256 1.5451 29.9741
Hep-G2/C3A CCLE 2.0378 4.6949 1.26 12.1301
PLC/PRF/5 CTRP2; CCLE 2.3577 5.3523 2.1866 25.1467
SNU-449 CCLE 2.7702 6.424 1.0929 10.9049
JHH-4 CTRP2; CCLE 2.928 7.6757 2.0915 23.758
SNU-182 CTRP2; CCLE 2.9684 12.1669 0.1527 29.8528
SNU-761 CTRP2 3.0681 11.2413 0.6834 28.0675
JHH-2 CTRP2; CCLE 3.1141 8.0223 2.1515 23.005
HLE CCLE 3.3795 8.7414 0.4391 12.8094
SNU-423 CTRP2; CCLE 4.6347 10.6307 2.4916 17.7734
HLF CTRP2; CCLE 4.6609 10.7674 2.4498 17.8732
HuH-1 CTRP2; CCLE 4.7474 10.5207 2.651 16.8871
JHH-1 CTRP2 4.8269 7.9105 3.9711 11.3893
SNU-387 CTRP2 5.1597 9.5697 3.4993 12.5257
SNU-398 CTRP2; CCLE 5.8654 12.7436 2.5444 14.8789
JHH-6 CTRP2; CCLE 6.0133 11.2009 3.4402 10.9791
SNU-886 CTRP2 6.7583 8.8015 5.2058 2.3615
SNU-475 CTRP2; CCLE 7.815 9.3782 5.5223 0.378
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 135 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2122 CCLE -0.8734 2.7877 -1.1711 34.4667
NCI-H1734 CTRP2 -0.6304 5.9251 -1.2078 45.3043
NCI-H1666 CCLE -0.2128 3.7673 -0.7422 29.8835
NCI-H2030 CTRP2; CCLE -0.0183 6.634 -0.7419 41.9208
NCI-H1648 CCLE 0.2218 3.8448 -0.2984 26.2041
NCI-H1355 CTRP2; CCLE 0.3121 6.9967 -0.4952 40.118
LCLC-97TM1 CTRP2 0.4252 14.423 -3.4173 43.3857
COLO 699 CTRP2; CCLE 0.4588 9.5161 -1.6243 38.2457
HCC2279 CTRP2 0.6445 7.4022 -0.2683 38.3591
NCI-H1341 CTRP2; CCLE 0.8475 4.6439 0.6847 35.138
NCI-H211 CTRP2; CCLE 0.8697 5.1885 0.6057 35.2959
NCI-H1568 CTRP2; CCLE 0.8847 9.1334 -0.6524 38.2644
IA-LM CCLE 0.9536 4.8425 0.0896 21.6665
NCI-H2405 CTRP2 1.1066 8.8825 -0.6814 33.8593
T3M-10 CCLE 1.2249 3.4205 0.9335 16.5866
NCI-H1915 CTRP2; CCLE 1.2335 7.5416 0.3206 34.7925
NCI-H23 CTRP2; CCLE 1.2671 5.4674 0.9762 32.7727
NCI-H2228 CTRP2; CCLE 1.2679 7.3838 0.413 34.4239
NCI-H1048 CCLE 1.2873 6.334 -0.2452 22.108
COLO 677 CCLE 1.2891 4.7722 0.467 18.6503
NCI-H1155 CTRP2 1.3255 6.3638 0.8039 33.1035
NCI-H2087 CCLE 1.382 4.6109 0.6328 17.505
NCI-H1581 CTRP2; CCLE 1.408 6.272 0.9206 32.4655
HCC44 CTRP2; CCLE 1.4411 6.7533 0.8107 32.6881
NCI-H1385 CTRP2 1.5023 4.3593 1.4256 30.5167
HCC1588 CTRP2 1.5062 5.9537 1.1162 31.5198
NCI-H1975 CTRP2; CCLE 1.5985 10.4333 -0.4441 35.4088
NCI-H358 CTRP2; CCLE 1.6663 10.4617 -0.3864 35.0623
SK-LU-1 CCLE 1.726 6.6601 0.0238 19.4147
Lu-99 CTRP2; CCLE 1.7411 6.4702 1.2252 30.3917
DMS 79 CTRP2 1.8337 9.5346 0.183 33.1445
NCI-H1838 CTRP2 1.8403 10.8879 -0.394 34.5285
GLC-82 CCLE 1.922 7.955 -0.4247 20.9279
COR-L23 CCLE 1.9774 4.7897 1.1561 12.8624
NCI-H1105 CTRP2 2.0331 6.1986 1.6237 28.1227
SW1271 CTRP2; CCLE 2.1265 7.2244 1.3969 28.5933
Hs 229.T CCLE 2.1601 4.7417 1.3584 11.2308
NCI-H520 CTRP2; CCLE 2.176 6.3606 1.7323 27.2991
HCC1833 CTRP2 2.28 10.1472 0.3823 31.2182
NCI-H841 CTRP2 2.292 9.1232 0.8342 29.8724
DMS 53 CTRP2 2.3786 5.4842 2.1817 25.0977
NCI-H1703 CTRP2 2.3898 6.8444 1.812 26.3592
DMS 273 CTRP2 2.4059 7.3431 1.6561 26.8508
NCI-H1573 CCLE 2.4251 6.0206 0.9874 12.4097
RERF-LC-A1 CTRP2; CCLE 2.4496 9.588 0.8002 29.4979
NCI-H1793 CTRP2; CCLE 2.4589 10.0617 0.6034 30.0535
NCI-H1694 CTRP2; CCLE 2.5059 6.4478 2.0655 25.1109
DMS 454 CTRP2 2.5472 4.7878 2.4832 23.5151
NCI-H2170 CCLE 2.5513 7.3228 0.4541 14.8464
NCI-H2141 CTRP2 2.5551 6.8676 1.9836 25.251
NCI-H1869 CTRP2; CCLE 2.574 8.9526 1.2003 27.8728
NCI-H1373 CCLE 2.602 7.1903 0.5646 14.1392
NCI-H1693 CTRP2; CCLE 2.6443 5.1685 2.531 23.0385
SK-MES-1 CTRP2 2.6641 6.8722 2.1002 24.5069
NCI-H661 CTRP2; CCLE 2.6798 7.2053 2.0008 24.8148
NCI-H2085 CCLE 2.6812 5.8216 1.3155 9.9488
NCI-H292 CTRP2 2.6884 7.0932 2.05 24.6136
NCI-H1092 CCLE 2.7018 6.6537 0.9191 12.0122
NCI-H650 CTRP2; CCLE 2.7652 9.3435 0.7902 24.038
HOP-62 CTRP2 2.7761 5.7789 2.5464 22.5693
NCI-H226 CTRP2; CCLE 2.8078 6.7159 2.3084 23.3271
NCI-H2106 CTRP2 2.8282 6.17 2.4994 22.5766
LC-1/sq-SF CCLE 2.8458 4.5951 2.0706 5.4335
NCI-H1395 CTRP2 2.8517 6.3517 2.4715 22.6056
SBC-5 CTRP2; CCLE 2.8734 5.0354 2.798 21.3814
Calu-3 CTRP2; CCLE 2.9327 6.813 2.4113 22.5813
NCI-H2172 CTRP2; CCLE 2.9524 5.7125 2.7546 21.2835
NCI-H446 CTRP2 2.9913 7.5508 2.207 23.1548
NCI-H1944 CTRP2; CCLE 3.0195 6.0914 2.7303 21.1638
SW900 CCLE 3.0571 5.0907 2.0018 5.2683
NCI-H1563 CTRP2; CCLE 3.0648 6.2605 2.7312 21.023
PC-14 CTRP2 3.0763 7.2685 2.4044 22.1851
NCI-H1651 CCLE 3.2202 8.3318 0.5153 12.804
NCI-H3255 CCLE 3.2613 8.1266 0.6511 12.0045
VMRC-LCD CCLE 3.3354 5.9496 1.7945 5.7435
RERF-LC-MS CTRP2; CCLE 3.4264 7.127 2.8327 19.5852
COR-L105 CTRP2; CCLE 3.5383 8.3521 2.4583 20.684
NCI-H1792 CTRP2; CCLE 3.5454 13.5543 0.0468 28.6006
LUDLU-1 CTRP2; CCLE 3.5629 11.2493 1.1664 25.2165
NCI-H810 CCLE 3.5658 6.7377 1.5792 6.3979
NCI-H2291 CTRP2 3.6437 9.9262 1.8635 22.6023
NCI-H647 CCLE 3.6518 5.6114 2.1894 3.0106
EKVX CTRP2 3.6953 6.5305 3.3333 16.9396
NCI-H522 CTRP2; CCLE 3.7136 7.2915 3.0775 17.848
NCI-H2444 CTRP2; CCLE 3.7311 7.7957 2.8934 18.5023
HCC1438 CTRP2 3.8271 8.5074 2.6891 19.0282
SHP-77 CTRP2; CCLE 3.8861 6.182 3.65 15.2096
Lu-65 CTRP2 3.8904 7.5961 3.1429 17.1085
NCI-H69 CTRP2 4.0401 7.928 3.1602 16.637
EBC-1 CTRP2; CCLE 4.0423 9.8596 2.2893 19.9977
NCI-H2342 CTRP2 4.0744 7.9812 3.1728 16.4966
NCI-H2081 CTRP2 4.1139 8.4307 3.016 17.006
NCI-H526 CTRP2 4.1305 12.918 0.9062 24.6102
NCI-H727 CTRP2; CCLE 4.1625 9.7353 2.4657 19.0227
NCI-H1339 CTRP2; CCLE 4.2308 9.1597 2.8016 17.5475
A-549 CTRP2; CCLE 4.3198 12.3765 1.347 22.703
HCC15 CTRP2; CCLE 4.3519 12.459 1.3366 22.6607
NCI-H1184 CCLE 4.363 7.6657 1.6817 4.3764
HOP-92 CTRP2 4.3965 6.9147 3.9511 12.6055
NCI-H196 CTRP2 4.3996 12.4668 1.3771 22.4083
CAL-12T CTRP2 4.4087 13.9912 0.6372 24.7731
NCI-H838 CTRP2 4.41 7.1396 3.8764 12.8553
COR-L51 CTRP2 4.4868 7.2409 3.9157 12.494
NCI-H2110 CTRP2 4.5233 10.5971 2.4027 18.3811
NCI-H2023 CTRP2; CCLE 4.7911 9.0541 3.3999 13.7865
HCC2108 CTRP2 4.8088 20.1448 -2.0603 30.4785
COR-L95 CTRP2 4.8593 8.268 3.8379 11.8466
HCC1171 CTRP2 5.0901 29.4107 -6.4432 36.1073
HCC366 CTRP2 5.1838 11.0383 2.7984 15.3141
NCI-H322 CTRP2; CCLE 5.263 8.8554 3.9444 10.4589
HCC4006 CTRP2; CCLE 5.2943 9.5679 3.6242 11.7111
NCI-H889 CTRP2 5.3104 9.5836 3.6312 11.647
DMS 114 CTRP2; CCLE 5.4033 10.9713 3.0282 13.9143
NCI-H2196 CTRP2 5.4346 10.7336 3.1741 13.2551
COR-L88 CTRP2 5.5112 10.2496 3.4824 11.8269
NCI-H1650 CTRP2; CCLE 5.6142 10.8026 3.298 12.3696
NCI-H1299 CTRP2; CCLE 5.6361 14.2763 1.5834 18.9228
HCC2935 CTRP2; CCLE 5.6808 6.4922 5.4748 3.2031
KNS-62 CTRP2; CCLE 5.9083 10.0624 3.9209 9.1869
HCC1195 CTRP2 5.9913 22.0964 -2.0259 28.0588
Calu-1 CTRP2; CCLE 6.0554 9.3574 4.3971 6.9026
LCLC-103H CTRP2; CCLE 6.2974 8.4343 4.2447 1.6904
HARA [Human squamous cell lung carcinoma] CTRP2; CCLE 6.3415 14.6295 1.9968 16.0181
NCI-H2009 CTRP2; CCLE 6.8525 17.6476 0.9017 18.8238
BEN CTRP2 7.1527 8.0879 5.7339 0.2023
RERF-LC-Ad1 CTRP2 7.2824 14.9603 2.5715 12.1543
MOR/CPR CTRP2 7.644 8.5856 5.7423 0.0675
HCC95 CTRP2 7.7617 22.1273 -0.6145 21.5977
NCI-H460 CTRP2; CCLE 7.8189 12.5422 4.1286 5.1967
HCC78 CTRP2; CCLE 8.3105 13.9436 3.7859 5.8867
LOU-NH91 CTRP2; CCLE 9.3023 25.9281 -1.3303 20.9309
HCC827 CTRP2 9.9016 24.1992 -0.054 16.7537
NCI-H441 CTRP2; CCLE 10.8799 21.0546 2.084 8.8815
NCI-H2286 CTRP2; CCLE 11.1505 22.1253 1.756 9.6388
Hs 888.Lu CTRP2 3.1696 14.56 -0.7954 31.6529
⏷ Show the Full List of 135 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.1823 10.1333 -1.7971 42.6036
COV434 CTRP2 -2.3829 6.5481 -3.2949 54.46
EFO-27 CCLE -0.2484 5.6344 -1.4974 32.9031
EFO-21 CCLE -0.0106 3.6377 -0.4794 27.9319
HEY A8 CCLE 0.1237 4.3514 -0.5894 27.8738
ES-2 CCLE 0.3277 3.1691 0.0358 24.2637
A2780 CCLE 0.4115 4.4527 -0.3214 25.575
SNU-119 CTRP2 0.415 9.1861 -1.172 40.8898
COV504 CCLE 0.5341 5.3785 -0.5748 26.2399
OVCAR-3 CCLE 0.6866 4.3428 0.0141 22.9931
OV-90 CTRP2; CCLE 0.7345 3.2476 0.7127 35.4465
SK-OV-3 CTRP2; CCLE 1.5318 11.1658 -0.8323 36.4366
OC 315 CCLE 1.5897 4.2724 0.9931 14.9814
OVCAR-4 CCLE 1.7018 3.7992 1.3063 13.0222
OC 314 CTRP2; CCLE 1.8632 5.3768 1.6448 28.5958
TOV-112D CTRP2; CCLE 1.882 4.7188 1.7831 28.0644
TYK-nu CCLE 2.0066 7.6227 -0.1837 19.5556
OC 316 CCLE 2.0992 5.36 1.0052 13.272
JHOS-4 CCLE 2.1021 4.2793 1.5152 10.5993
ONCO-DG-1 CTRP2; CCLE 2.4392 8.2135 1.361 27.7489
TOV-21G CTRP2; CCLE 2.5499 10.535 0.486 30.1216
OVMANA CCLE 2.5965 10.4682 -1.0754 21.801
OV7 CTRP2 2.6827 11.8942 -0.0015 31.0614
MCAS CCLE 2.9154 7.9863 0.436 13.9732
IGROV-1 CTRP2; CCLE 3.2055 10.382 1.2164 26.015
Kuramochi CTRP2; CCLE 3.6254 8.4828 2.4922 20.3195
OVCAR-5 CTRP2 3.6454 6.3376 3.3407 17.06
SNU-8 CTRP2 3.7106 9.7534 2.0097 21.8947
OAW28 CTRP2 3.7706 10.3023 1.8149 22.4447
JHOS-2 CTRP2; CCLE 3.8407 9.6218 2.2001 20.8505
OVTOKO CTRP2; CCLE 4.2147 14.5591 0.1802 26.5718
OAW42 CTRP2 4.8626 7.3482 4.2599 10.145
COV318 CCLE 4.934 12.5834 -0.2912 12.9593
OV56 CTRP2 5.1534 12.5803 2.0071 18.4291
FU-OV-1 CTRP2; CCLE 5.2059 12.9097 1.8902 18.7438
OVCAR-8 CTRP2; CCLE 5.2659 9.8723 3.4484 12.498
OVSAHO CTRP2; CCLE 5.6448 11.103 2.4998 10.227
RMG-I CTRP2 6.0739 14.9505 1.6158 17.9152
ES2 CTRP2 6.5432 15.9634 0.7781 15.5166
DOV13 CTRP2; CCLE 6.7622 9.0465 4.2287 1.3008
Caov-3 CTRP2 6.7873 20.7264 -0.6871 23.5046
OVISE CTRP2 7.9163 13.6017 2.8561 5.2342
COV644 CTRP2 8.1577 12.0694 4.5576 3.1577
JHOC-5 CTRP2 10.6657 21.3572 1.8112 10.0329
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.9891 8.4986 2.8586 17.946
Aska-SS CTRP2 8.532 18.9389 1.5344 13.8862
A-204 CTRP2; CCLE -0.939 4.8278 -1.2824 46.9031
GCT CTRP2; CCLE 0.4484 4.6755 0.2492 37.8663
G-402 CTRP2; CCLE 0.4731 3.2524 0.4425 37.2146
TE 617.T CTRP2; CCLE 0.6754 4.7825 0.475 36.3829
G-401 CTRP2; CCLE 0.7984 5.9866 0.335 36.319
HT-1080 CTRP2; CCLE 1.0269 4.9886 0.8165 34.1017
SK-LMS-1 CTRP2 1.1562 7.3438 0.3058 35.103
TTC-709 CTRP2 1.1748 8.8948 -0.2502 36.3961
Rh30 CCLE 1.732 4.1873 1.1772 13.5641
TE 441.T CTRP2 1.9263 6.075 1.5418 28.7418
Rh41 CTRP2 1.9464 3.7453 1.9355 27.338
RD CTRP2; CCLE 2.0976 5.8692 1.7837 27.3691
SW982 CTRP2 2.7505 15.9892 -1.8833 34.9102
MES-SA CTRP2; CCLE 3.0124 5.0707 2.9415 20.4403
Hs 729.T CTRP2; CCLE 3.2218 9.3031 1.7187 24.2589
KYM-1 CTRP2 3.8274 5.1382 3.7991 14.8654
SK-UT-1 CTRP2 5.217 12.6566 2.0257 18.2204
BT-16 CTRP2 5.5162 10.127 3.5478 11.546
Tm87-16 CTRP2 5.9987 14.8052 1.6259 18.0301
RKN CTRP2; CCLE 6.2113 13.8817 2.2639 15.2723
BT-12 CTRP2 6.4069 10.5615 4.0804 7.5782
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 7.7791 17.8925 1.4966 15.2217
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
L3.3 CCLE -0.0714 3.4471 -0.4838 28.1975
HuP-T4 CCLE 0.5357 5.2892 -0.5348 26.0586
SUIT-2 CTRP2; CCLE 0.8083 6.4016 0.2286 36.5636
Panc 03.27 CTRP2; CCLE 0.8839 4.6722 0.7191 34.9043
PK-1 CCLE 1.0719 6.5779 -0.5713 24.3103
Hs 766T CTRP2; CCLE 1.1555 6.7904 0.4881 34.6109
PK-59 CCLE 1.3252 5.7683 0.0556 20.5524
HPAC CCLE 1.3839 6.3189 -0.1435 21.3115
KP-4 CTRP2; CCLE 1.4656 5.4179 1.2035 31.3732
PK-45H CCLE 1.6137 6.8614 -0.1801 20.7445
SW1990 CTRP2; CCLE 2.1501 7.1022 1.4649 28.2917
PSN1 CTRP2 2.1764 6.7391 1.6149 27.701
MIA PaCa-2 CTRP2; CCLE 2.342 6.1164 1.984 25.9045
KP-1N CCLE 2.5164 5.2801 1.4355 9.7613
KP-1NL CCLE 2.5226 4.851 1.6517 8.5871
SU.86.86 CTRP2; CCLE 2.5732 6.8431 2.0115 25.0973
KP-3 CTRP2; CCLE 2.6083 11.0362 0.3186 30.4201
Capan-2 CTRP2; CCLE 2.6107 4.0587 2.6036 22.8995
Panc 10.05 CCLE 2.7945 5.8262 1.4122 9.1262
AsPC-1 CTRP2; CCLE 2.9334 8.8456 1.6198 25.4165
PL45 CCLE 3.0723 5.2604 1.9295 5.6232
DAN-G CTRP2 3.3335 10.2816 1.3905 25.0851
QGP-1 CTRP2 3.4885 7.709 2.2661 16.1297
BxPC-3 CTRP2 3.8501 18.7991 -2.2427 32.8992
HPAF-II CTRP2; CCLE 4.0057 10.6591 1.3305 18.7088
KP-2 CTRP2; CCLE 4.0978 9.4825 2.5199 18.9776
TCC-Pan2 CTRP2 4.1653 8.3953 3.084 16.606
Capan-1 CTRP2 4.2135 8.5399 3.068 16.5447
Panc 04.03 CTRP2; CCLE 4.3125 8.2277 3.3085 15.3406
PaTu 8988t CTRP2 4.5911 7.6324 3.8567 12.4487
Panc 08.13 CTRP2 5.9507 13.208 2.3842 15.3278
HuP-T3 CTRP2; CCLE 6.1061 12.4029 2.9164 12.9302
Panc 02.03 CTRP2; CCLE 6.3659 10.6052 4.026 7.8788
PaTu 8902 CTRP2 6.4365 11.5592 3.6066 9.4939
Panc 05.04 CTRP2 6.5682 20.5306 -0.767 24.113
CFPAC-1 CTRP2 7.8266 9.2658 5.5692 0.2781
SNU-213 CTRP2 7.8293 16.2463 1.5599 10.4425
SNU-410 CTRP2 8.109 9.8753 5.457 0.3956
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes2 CCLE -1.7988 3.112 -2.268 42.4563
MSTO-211H CTRP2; CCLE -0.9279 5.8661 -1.5167 47.0284
NCI-H2452 CTRP2; CCLE -0.1938 8.415 -1.5316 43.751
NCI-H2052 CTRP2; CCLE 0.3121 10.26 -1.7123 42.0252
NCI-H28 CTRP2; CCLE 1.4915 5.8488 1.1277 31.5319
IST-Mes1 CTRP2; CCLE 2.8082 8.7264 1.5398 26.0527
ACC-MESO-1 CTRP2 2.8103 4.471 2.7896 21.6156
MPP 89 CTRP2; CCLE 4.4104 10.9659 2.1174 19.7334
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 CCLE 2.6753 9.1706 -0.3599 18.4845
NCI-H660 CTRP2 3.0372 5.8027 2.8253 20.7693
DU145 CTRP2; CCLE 4.6306 13.1137 1.272 22.2178
22Rv1 CTRP2; CCLE 5.4129 12.8618 1.4383 15.1477
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.3483 8.2645 0.179 34.7638
A-253 CTRP2; CCLE 2.2741 5.7862 1.9973 26.0705
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 -4.5348 0.9426 -4.6054 68.1227
SNU-16 CTRP2; CCLE 0.3967 3.8802 0.3092 37.8924
AZ-521 CCLE 0.4239 4.264 -0.2351 25.1355
HGC-27 CTRP2; CCLE 0.69 6.1542 0.1706 37.1541
SNU-1 CTRP2; CCLE 1.0371 4.4397 0.9195 33.7423
MKN74 CCLE 1.3996 6.0561 -0.0046 20.5969
GSS CTRP2 1.411 7.4108 0.5583 33.5271
KATO III CTRP2 1.5686 6.301 1.0873 31.4036
NCI-N87 CTRP2; CCLE 1.6037 7.6967 0.6643 32.5735
Fu97 CTRP2; CCLE 1.8564 5.7312 1.5554 28.9211
OCUM-1 CCLE 2.2973 8.7222 -0.4659 20.0164
SH-10-TC CCLE 2.3182 6.9973 0.4082 15.7318
SNU-216 CTRP2 2.4587 4.2515 2.4388 23.9551
Hs 746.T CTRP2; CCLE 2.4657 8.4515 1.2936 27.8919
NUGC-4 CTRP2; CCLE 2.6651 5.5408 2.4807 23.1479
GCIY CCLE 2.7328 4.5197 2.0074 6.0823
SNU-601 CTRP2 2.8941 4.9192 2.8356 21.1856
BGC-823 CCLE 3.0287 6.2478 1.4 8.5942
MKN7 CCLE 3.2016 7.7257 0.803 11.3565
SNU-620 CTRP2 3.202 6.064 2.9371 19.8629
NUGC-3 CTRP2; CCLE 3.2036 10.2535 1.2732 25.8325
23132/87 CTRP2 3.2658 7.2864 2.6009 20.911
SNU-668 CTRP2 3.3511 7.6351 2.5574 20.831
HuG1-N CTRP2 3.6377 8.5889 2.4588 20.4128
RERF-GC-1B CCLE 3.7242 7.0023 1.5656 6.1421
SNU-719 CTRP2 3.8457 12.6032 0.7911 25.6806
ECC12 CTRP2 3.86 10.2486 1.9279 21.805
MKN1 CTRP2 3.9543 7.8752 3.0935 17.1258
SNU-5 CTRP2 3.9544 8.2956 2.9125 17.8276
KE-39 CTRP2; CCLE 4.2497 8.3554 3.1876 15.98
LMSU CTRP2 4.6046 9.5345 2.9909 15.8785
GSU CTRP2 4.8105 6.9242 4.386 9.7891
MKN45 CTRP2; CCLE 5.9916 7.2288 4.604 0.6855
AGS CTRP2 7.9522 9.6497 5.4769 0.4182
IM95 CTRP2; CCLE 8.2247 10.6345 5.2115 0.938
SNG-M CTRP2; CCLE 0.1808 4.4813 -0.0057 39.5789
SNU-1077 CTRP2 5.3442 13.0459 1.9443 18.2444
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2; CCLE 0.3473 6.846 -0.4091 39.8075
8505C CTRP2; CCLE 0.5133 4.4388 0.3585 37.3169
B-CPAP CTRP2; CCLE 1.2553 8.4426 0.0116 35.5026
FTC-238 CTRP2 1.5135 7.2983 0.7083 32.7474
CGTH-W-1 CTRP2 1.6237 6.3025 1.1471 31.0299
SW579 CTRP2; CCLE 1.9243 7.8131 0.9659 30.6209
BHT-101 CTRP2 2.0997 6.4913 1.6096 27.9599
TT2609-C02 CTRP2; CCLE 2.6648 10.0083 0.8376 28.7481
ML-1 [Human leukemia] CTRP2 2.7638 23.9386 -5.7649 39.7053
TT CTRP2 2.8634 11.9723 0.1407 30.177
CAL-62 CTRP2 5.5322 13.4341 1.9145 17.9525
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 840.T CCLE -0.0501 5.7859 -1.3548 31.5987
PE/CA-PJ15 CTRP2 0.3685 8.1952 -0.8464 40.5372
YD-10B CTRP2 0.7181 7.942 -0.3782 38.3172
SCC-25 CCLE 0.9057 3.1606 0.6686 19.0622
SNU-1214 CTRP2 1.0014 8.8823 -0.4294 37.3958
SNU-46 CTRP2 1.7043 6.8839 1.0547 31.0576
SNU-899 CTRP2 1.9329 11.8356 -0.7243 34.9668
FaDu CTRP2; CCLE 1.9422 6.7221 1.3657 29.2808
PE/CA-PJ49 CTRP2 2.0895 4.4453 2.0372 26.5241
SCC-9 CTRP2; CCLE 2.1338 7.1326 1.4367 28.4375
PE/CA-PJ34 (clone C12) CTRP2 2.9935 10.5466 0.9286 27.5259
CAL-27 CTRP2; CCLE 3.0375 6.8989 2.4953 21.9646
PE/CA-PJ41 (clone D2) CTRP2 3.1583 6.8313 2.6495 21.043
HSC-4 CTRP2 3.2808 8.4683 2.1413 22.5731
Detroit 562 CTRP2; CCLE 3.3731 10.4495 0.848 22.1705
YD-8 CTRP2 3.4337 12.1794 0.5999 27.3271
BHY CTRP2 3.7096 12.3404 0.7881 26.0375
BICR 22 CTRP2 3.7638 11.161 1.4036 23.9007
HSC-2 CTRP2; CCLE 4.5291 8.066 3.6008 13.6247
CAL-33 CTRP2 4.6487 10.5733 2.5327 17.5809
BICR 31 CTRP2 4.7672 15.0751 0.425 24.5766
BICR 18 CTRP2 5.2646 11.3561 2.7137 15.4731
SCC-4 CTRP2 5.2969 16.5573 0.1527 24.1976
BICR 56 CTRP2 5.9608 6.6288 5.6799 1.7014
HSC-3 CTRP2 7.2755 22.6295 -1.965 22.5858
BICR 16 CTRP2 7.4667 14.2268 3.0695 9.9145
SNU-1041 CTRP2 7.9169 17.0226 1.2471 11.4947
SNU-1066 CTRP2 8.2037 16.8331 1.5294 10.0125
SNU-1076 CTRP2 8.4423 21.9895 -0.0286 18.8855
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2; CCLE 0.8725 8.6488 -1.7472 28.9269
JMSU-1 CTRP2; CCLE 1.3452 7.4669 0.4676 34.0066
HT-1376 CTRP2; CCLE 2.0025 12.21 -0.8248 34.9673
RT-4 CTRP2; CCLE 2.0079 6.8064 1.4099 28.9242
KMBC-2 CTRP2; CCLE 2.0568 5.0226 1.923 27.0202
RT-112 CCLE 2.2252 4.3327 1.6137 9.6915
5637 CTRP2; CCLE 2.3669 15.1191 -1.8312 35.8291
SW780 CCLE 2.426 5.7367 1.1281 11.6595
SCaBER CTRP2; CCLE 2.4564 9.0152 1.0512 28.702
T24 CTRP2; CCLE 2.6808 9.4118 1.1151 27.8327
J82 CTRP2; CCLE 3.5746 7.2828 2.9326 18.7883
UM-UC-1 CTRP2 3.5898 8.8338 2.3022 21.1312
BC-3C CTRP2 4.0867 12.2159 1.2064 23.7456
U-BLC1 CTRP2 4.1086 10.8649 1.8779 21.3565
KU-19-19 CTRP2 4.3594 11.1945 1.9586 20.4452
UM-UC-3 CCLE 4.3615 8.6363 1.2199 6.7172
VM-CUB-1 CTRP2 4.3627 10.0726 2.501 18.3909
253J-BV CTRP2 4.7579 7.4252 4.1187 10.977
647V CTRP2 4.8075 9.8033 3.0556 15.1379
TCCSUP CTRP2; CCLE 5.1292 12.5823 1.9846 18.5661
SW1710 CTRP2 5.1598 9.2605 3.6505 11.9044
BFTC-905 CTRP2 5.3394 7.0439 4.8809 6.4466
CAL-29 CTRP2 5.4784 7.7462 4.6856 6.9069
639V CTRP2; CCLE 5.9904 10.1407 3.9511 8.8992
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.6431 8.5147 5.7659 0.0466

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5674).
2 RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications. Invest New Drugs. 2013 Feb;31(1):200-5.